PX43 BIO & FS6 Intelligent Inverted Microscope Series: Upgraded with New and Improved Objectives and Phase Contrast Imaging

Posted by Motic America on July 21, 2025

Motic's PX43 BIO & FS6 Series are intelligent inverted microscopes. The PX43 features our CCIS infinity corrected optical system, OLED display, quintuple encoded nosepiece and Motic Analysis Bio software for excellent imaging quality. The PX43 comes standard with bright-field and phase contrast observation modes. The PX43 FS6 adds fluorescence to the capabilities. A new generation of professional image analysis software, Analysis Bio with it’s simple and intuitive interface, is rich in functions and easy to use. The software provides a wide range of functions and measurement tools for a variety of applications, which greatly improves the user's work efficiency.

Model	PX43 BIO	PX43 FS6

Descriptions	PX43BIO is an intelligent inverted microscope optimized for brightfield and phase contrast. With a long working distance, ergonomic design, and seamless software integration, it’s ideal for routine live-cell imaging, delivering high-quality images and enhanced workflow efficiency through automated objective recognition and real-time status display.	PX43FS6 expands PX43BIO’s capabilities with advanced fluorescence imaging. It features a coded 5+1 fluorescence turret, adjustable light shields, and compatibility with LED and mercury-based light sources. Designed for multi-channel fluorescence and live-cell analysis, it offers superior optical performance for research in biology, immunology, and medicine.
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PX43 Series Features

Ergonomic Observation Tubes	Large Working Distance
The observation tube can be rotated 360°, allowing users to adjust thee viewing angle to their preference. This ergonomic design helps users maintain a natural posture during operation and reduces fatigue during extended periods of use.	The PX43 offers a generous 72mm working distance, providing ample space for a wide variety of cell culture containers, enhancing flexibility and ease of use.

Adjustable UV Shield	Interchangeable Transmitted Light Source
The PX43 FS6 comes equipped with an adjustable UV shield, allowing users to adjust its position based on personal preference and specific applications, effectively protecting their eyes from UV light exposure.	Users can choose between a 50W halogen lamp or a 10W LED light source for transmitted illumination. Both options deliver a bright, uniform field of view and can be easily swapped depending on the application’s requirements.

Coded 5+1 Fluorescence Filter Turret	5-Position Coded Nosepiece
The PX43 FS6 features a smart 5+1-channel coded fluorescence turret, pre-installed with high-quality DAPI, FITC, and TRITC filters. It supports up to five fluorescence channels and one brightfield channel, allowing for efficient multi-channel imaging.	The PX43 includes a 5-position coded nosepiece which allows the microscope to display which objective is currently used. This information can be embedded in the image metadata with Analysis Bio, allowing for easier image tracking and improving workflow efficiency.

Real-time Microscope Status Display	Multiple Vessel Holder Options
A front-facing OLED display with an intuitive user interface shows real-time microscope status, including objective magnification, illumination intensity, and filter settings. The display also updates in real-time with user adjustments.	The PX43 comes standard with a hard-coated stage and offers an optional mechanical stage. It supports various interchangeable vessel holders to accommodate a wide range of cell culture vessels, including flasks, Petri dishes, and 96-well plates, meeting diverse sample observation needs.

Multifunction Control Knob
This integrated knob streamlines microscope control, enabling quick access to several key settings. This multifunctional design significantly enhances operational efficiency. Light Source Selection: Easily switch between transmitted and reflected light sources. ECO time setting: Configure sleep mode and automatic wake-up time. Objective Configuration: Includes light memory and auto- recognition of objective changes. Filter Configuration: Customize and select filter channels as needed.

Setting	Light source setting	ECO setting	Objectives setting	Filter cubes setting
Wide Selection of Fluorescent Light Sources
The PX43 FS6 can be used with fluorescent LED lamps such as the LUMOS3 and metal halide lamps such as the LUMOS X, in addition to traditional mercury lamps. ▶ LUMOS3: LED light source, average lifespan up to 20,000h. Low phototoxicity, 3-channel LED fluorescence. Each channel is independently controlled and can adjust automatically when switching filters. ▶ LUMOS X: Metal halide light source, average lifespan up to 3,000h, 90s warm-up, adjustable light intensity. The light source status and cumulative hours of use can be displayed, making it easy for the user to check how long it has been running.
LUMOS3
LUMOS X